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T2 Prostate Cancer Trial (Complete) - Canada
In Spring, 2002, Oncolytics initiated a clinical trial examining the use of REOLYSIN®
in cancer confined to the prostate gland. The primary endpoints of this study
were to examine safety and the histopathology of prostate tissue post-therapy and post-prostactectomy.
Patients were treated with a single injection of REOLSYIN® directly into the prostate gland.
Final results showed evidence of apoptotic tumour cell death in four of six patients, with no
safety concerns. A fifth patient saw PSA level drop by 53% and the prostate gland shrank by 67%
from just prior to injection to surgical removal of the prostate gland three weeks later.
See related press releases:
February
27, 2004 - Oncolytics Biotech Provides Final Update on T2 Prostate Cancer Study
March
31, 2003 - Oncolytics Biotech Inc. Reports Presentation of
Results From Interim Assessment of T2 Prostate Cancer Trial
April
16, 2002 - Oncolytics Biotech Inc. Starts First Patient Treatment
In Prostate Cancer Trial
October
11, 2001 - Oncolytics Biotech Inc. Announces Approval to Proceed
with Clinical Trial to Evaluate REOLYSIN® for the Treatment
of Prostate Cancer
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