Oncolytics Biotech® Inc. Announces Progression Free Survival Data for Phase 2 Study of REOLYSIN® in Squamous Cell Lung Cancer

CALGARY, Oct. 22, 2013 /PRNewswire/ – Oncolytics Biotech Inc. (“Oncolytics”)
(TSX:ONC) (NASDAQ:ONCY) today announced that a poster presentation
covering progression free survival (PFS) and final tumour response data
from its U.S. Phase 2 single arm clinical trial in patients with
squamous cell carcinoma of the lung (SCCLC) using intravenous
administration of REOLYSIN in combination with carboplatin and
paclitaxel (REO 021), is being made today at the AACR-NCI-EORTC
International Conference on Molecular Targets and Cancer Therapeutics.
The conference is being held in Boston, MA from October 19-23.

The investigators reported that there were 25 evaluable patients, each
of whom had received between two and 12 cycles of therapy.  Of the
evaluable patients who had more than one cycle of therapy, 23 (92%)
exhibited overall tumour shrinkage. When evaluated for best response,
which is the best percentage response recorded on study compared to
baseline, 10 patients (40%) had partial responses (PRs), while a
further 14 (56%) showed stable disease (SD), and one (4%), had
progressive disease (PD). Using RECIST criteria to evaluate best
overall response, 10 patients (40%) had partial responses (PRs), 12
(48%) showed stable disease (SD) and three (12%), had progressive
disease (PD).  31.8% of patients with sufficient follow up had a PFS
greater than six months. A copy of the poster presentation, which
includes a waterfall graph showing individual patient data, will be
available on the Company’s website at http://www.oncolyticsbiotech.com/presentations.

About Lung Cancer

The American Cancer Society estimates that in 2013, approximately
228,190 new cases of lung cancer will be diagnosed. Between 85% and 90%
of all lung cancers are classified as non-small cell lung cancer
(NSCLC); squamous cell carcinomas account for 25-30% of all lung
cancers. Lung cancer is by far the leading cause of cancer death among
both men and women. There will be an estimated 159,480 deaths from lung
cancer in the United States in 2013, accounting for around 27% of all
cancer deaths. Lung cancer is the leading cause of cancer death, with
more people dying each year of lung cancer than from colon, breast, and
prostate cancers combined. For more information about lung cancer,
please go to www.cancer.org.

About Oncolytics Biotech Inc.

Oncolytics is a Calgary-based biotechnology company focused on the
development of oncolytic viruses as potential cancer therapeutics. 
Oncolytics’ clinical program includes a variety of human trials
including a Phase III trial in head and neck cancers using REOLYSIN®, its proprietary formulation of the human reovirus. For further
information about Oncolytics, please visit: www.oncolyticsbiotech.com.

This press release contains forward-looking statements, within the
meaning of Section 27A of the Securities Act of 1933, as amended, and
Section 21E of the Securities Exchange Act of 1934, as amended.
Forward-looking statements, including the Company’s expectations
related to the U.S. Phase II squamous cell carcinoma lung cancer trial,
future trials in this indication, and the Company’s belief as to the
potential of REOLYSIN as a cancer therapeutic, involve known and
unknown risks and uncertainties, which could cause the Company’s actual
results to differ materially from those in the forward-looking
statements. Such risks and uncertainties include, among others, the
availability of funds and resources to pursue research and development
projects, the efficacy of REOLYSIN as a cancer treatment, the
tolerability of REOLYSIN outside a controlled test, the success and
timely completion of clinical studies and trials, the Company’s ability
to successfully commercialize REOLYSIN, uncertainties related to the
research, development and manufacturing of pharmaceuticals, changes in
technology, general changes to the economic environment and
uncertainties related to the regulatory process. Investors should
consult the Company’s quarterly and annual filings with the Canadian
and U.S. securities commissions for additional information on risks and
uncertainties relating to the forward-looking statements. Investors
should consider statements that include the words “believes”,
“expects”, “anticipates”, “intends”, “estimates”, “plans”, “projects”,
“should”, or other expressions that are predictions of or indicate
future events or trends, to be uncertain and forward-looking. Investors
are cautioned against placing undue reliance on forward-looking
statements. The Company does not undertake to update these
forward-looking statements, except as required by applicable laws.

SOURCE Oncolytics Biotech Inc.